November 8, 2017

How much marijuana would it take to kill you

Nearly half of Americans say they have tried marijuana at least once in their life.With more people lighting up than ever and nine states voting on the legalization of marijuana, it’s important to remember how many fatally overdose on the drug. That’s according to the Centers for Disease Control and Prevention which collects data on a range of other substances, both legal and illicit, and the Drug Enforcement Administration. For comparison, opioids, which include prescription pain relievers and heroin, killed more than 20000 Americans in 2014. Nearly 80000 people die from alcohol-related causes every year, which makes alcohol the fourth leading preventable cause of the death in the US. It’s pretty impossible to ingest a lethal dose of marijuana. The User’s Guide spoke with experts and crunched the numbers on how much bud it would take to kill someone. Even aspirin can kill you if you take too much, but a fatal dose of marijuana would require ingestion of fifteen hundred pounds in fifteen minutes.  One reason for this impossibility is the way the brain works. When a user ingests marijuana, chemicals in the plant ride the nervous system to the brain and latch onto molecules called cannabinoid receptors as discussed by many Florida Marijuana Doctors deliberate. Those little holding cells influence pleasure, memory, coordination, and cognition, among other functions, which is why getting high affects thinking and behavior. Cannabinoid receptors are not found in the brainstem areas that control breathing. Thus, “lethal overdoses from cannabis and cannabinoids do not occur,” The National Cancer Institute explains. Marijuana isn’t harmless, however. The psychoactive ingredient that gets users high, tetrahydrocannabinol, or THC, is a powerful intoxicant. Having physical abilities and judgments impaired can lead users to put themselves in unsafe situations.  And while there are no recorded cases of deaths from marijuana overdose, one marijuana doctor in florida explains an oil rig too many can make users feel incredibly uncomfortable. Their heart starts to race, hands tremble, and anxiety strikes. There are things they can do to mitigate a “What I have done?” high. In his book, he recommends users tell themselves that they’re in no real danger. Drink some water to stay hydrated and eat a snack — preferably one that is ready-to-eat and does not require operating a stove to enhance your blood sugar.
November 2, 2017

Mental and Physical Effects While On Medical Marijuana

Since weed makes blood vessels expand, it can give you red eyes.  A case of the munchies is no figment of the imagination both casual and heavy marijuana users tend to overeat when they smoke. Marijuana may effectively flip a circuit in the brain that is normally responsible for quelling the appetite, triggering us to eat instead, according to a recent study of mice. It all comes down to a special group of cells in the brain that are normally activated after we have eaten a big meal to tell us we’ve had enough. The psychoactive ingredient in weed appears to activate just one component of those appetite-suppressing cells, making us feel hungry rather than satisfied.  Marijuana can mess with your memory by changing the way your brain processes information, but scientists still aren’t sure exactly how this happens. Several studies suggest that weed interferes with short-term memory, and researchers tend to see more of these effects in inexperienced or infrequent users than in heavy, frequent users. Unsurprisingly, these effects are most evident in the acute sense — immediately after use, when people are high. According to the new report, there was limited evidence showing a connection between cannabis use and impaired academic achievement, something that has been shown to be especially true for people who begin smoking regularly during adolescence said by many medical marijuana doctors in florida and other states. Importantly, in most cases, saying cannabis is connected to an increased risk doesn’t mean marijuana use caused that risk.  Scientists can’t say for sure whether marijuana causes depression or whether depressed people are simply more likely to smoke. But one study from the Netherlands suggests that smoking weed could raise the risk of depression for young people who already have a special serotonin gene that could make them more vulnerable to depression. Those findings are bolstered by the NASEM report, which found moderate evidence that cannabis use was linked to a small increased risk of depression. The report also found substantial evidence of an increased risk among frequent marijuana users of developing schizophrenia — something that studies have shown is a particular concern for people at risk for schizophrenia in the first place.  Researchers think it’s possible that CBD might be a useful treatment for anxiety disorders, and that’s something that several institutions are currently trying to study. In general, the recent report thought the evidence that Florida marijuana Dcotors increased the risk of most anxiety disorders was limited. However, the authors write that there is moderate evidence that regular marijuana use is connected to an increased risk of social anxiety. As in other cases, it’s hard to know whether marijuana use causes that increase or people use marijuana because of an increased risk of social anxiety.  Researchers think it’s possible that CBD might be a useful treatment for anxiety disorders, and that’s something that several institutions are currently trying to study. In general, the recent report thought the evidence that marijuana increased the risk of most anxiety disorders was limited. However, the authors write that there is moderate evidence that regular marijuana use is connected to an increased risk of social anxiety. As in other cases, it’s hard to know whether marijuana use causes that increase or people use marijuana because of an increased risk of social anxiety.

October 30, 2017

Multiple Benefits For Medicinal Marijuana

Despite the fact that the Drug Enforcement Agency categorizes marijuana as a schedule I drug, one that has no accepted medical use, a majority of Americans have thought medical pot should be legal since the late 1990s — and a majority now support recreational legalization as well.

29 states have legalized medical marijuana – that number is 43 states if we count laws with very limited access.

Even the NIH’s National Institute on Drug Abuse lists medical uses for cannabis.

But even though researchers have identified some fascinating potential benefits of medical marijuana so far, it’s something that’s still hard to study, making conclusive results tough to come by. The schedule I classification means it’s hard for researchers to get their hands on pot grown to the exacting standards that are necessary for Florida marijuana doctors and medical research, even in states where it’s legal. Plus, no researcher can even try to make an FDA-approved cannabis product while it has that DEA classification, which removes some motivation to study the plant.

More research would identify health benefits more clearly and would also help clarify potential dangers such as with any psychoactive substance, there are risks associated with abuse, including dependency and emotional issues. And many doctors want to understand marijuana’s effects better before deciding whether to recommend it or not.

There’s a fair amount of evidence that marijuana does no harm to the lungs, unless you also smoke tobacco, and one study published in Journal of the American Medical Association found that marijuana not only doesn’t impair lung function, it may even increase lung capacity.

Researchers and marijuana doctors in Florida looking for risk factors of heart disease tested the lung function of 5,115 young adults over the course of 20 years. Tobacco smokers lost lung function over time, but pot users actually showed an increase in lung capacity.

It’s possible that the increased lung capacity may be due to taking a deep breaths while inhaling the drug and not from a therapeutic chemical in the drug.

Those smokers only toked up a few times a month, but a more recent survey of people who smoked pot daily for up to 20 years found no evidence that smoking pot harmed their lungs.

With that caveat about research in mind, here are the medical benefits of marijuana.

Marijuana use can prevent epileptic seizures in rats, a 2003 study showed.

A professor gave marijuana extract and synthetic marijuana to epileptic rats. The drugs rid the rats of the seizures for about 10 hours. Cannabinoids like the active ingredients in marijuana, tetrahydrocannabinol (also known as THC), control seizures by binding to the brain cells responsible for controlling excitability and regulating relaxation.

The findings were published in the Journal of Pharmacology and Experimental Therapeutics.

During the research for his documentary interviewed the Figi family, who treats their daughter using a medical marijuana strain high in cannabidiol and low in THC.

There are at least two major active chemicals in marijuana that researchers think have medicinal applications (there are up to 79 known active compounds). Those two are cannabidiol (CBD) — which seems to impact the brain mostly without a high— and tetrahydrocannabinol (THC) — which has pain relieving (and other) properties.

The Figi family’s daughter, Charlotte, has Dravet Syndrome, which causes seizures and severe developmental delays.

According to the film, the drug has decreased her seizures from 300 a week to just one every seven days. Forty other children in the state are using the same strain of marijuana (which is high in CBD and low in THC) to treat their seizures — and it seems to be working.

The doctors who recommended this treatment say that the cannabidiol in the plant interacts with the brain cells to quiet the excessive activity in the brain that causes these seizures.

As Gutpa notes, a Florida hospital that specializes in the disorder, the American Academy of Pediatrics, and the Drug Enforcement agency don’t endorse marijuana as a treatment for Dravet or other seizure disorders.

CBD may also help prevent cancer from spreading, researchers at California Pacific Medical Center in San Francisco reported in 2007.

Cannabidiol stops cancer by turning off a gene called Id-1, the study, published in the journal Molecular Cancer Therapeutics, found. Cancer cells make more copies of this gene than non-cancerous cells, and it helps them spread through the body.

The researchers studied breast cancer cells in the lab that had high expression levels of Id-1 and treated them with cannabidiol. After treatment the cells had decreased Id-1 expression and were less aggressive spreaders. But beware: these are studies on cancer cells in the lab, not on cancer patients. 

Other very preliminary studies on aggressive brain tumors in mice or cell cultures have shown that florida medical marijauna THC and CBD can slow or shrink tumors at the right dose, which is a great reason to do more research into figuring out that dose.

One 2014 study found that marijuana can significantly show the growth of the type of brain tumor associated with 80% of malignant brain cancer in people.

Medical marijuana users claim the drug helps relieve pain and suppress nausea — the two main reasons it’s often used to relieve the side effects of chemotherapy.

Researchers at Harvard Medical School suggested that that some of the drug’s benefits may actually be from reduced anxiety, which would improve the smoker’s mood and act as a sedative in low doses.

Published in the journal Molecular Pharmaceutics, found that THC, the active chemical in marijuana, slows the formation of amyloid plaques by blocking the enzyme in the brain that makes them. These plaques seem to be what kill brain cells and potentially cause Alzheimer’s.

A synthetic mixture of CBD and THC seem to preserve memory in a mouse model of Alzheimer’s disease. Another study suggested that in population-based studies, a THC-based prescription drug called dronabinol was able to reduce behavioral disturbances in dementia patients. Get Started.

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All Natural MD is a medical cannabis clinic that conducts patient evaluations in the State of Florida to determine if one qualifies and can benefit from the use of medical cannabis. We have been established since 2016 and have close to 20,000 patients that are doing very well with the use of medical cannabis.