Can Medical Marijuana Help Treat Patients With Seizures?
A number of medical researches have been conducted on whether Medical Cannabis is useful for seizures or not while, various physical applications on the animal models have found that right. Doubtlessly, for the last few years, its importance in the medicines has skyrocketed. Research has shown that most of the medicines for epilepsy have a minor fraction of cannabis products and derivatives, so, that these are very powerful. The question often hits the brain that what researchers have found effective in Cannabis that successfully enables it to replace a number of medicinal components for seizures for over a decade? If it’s really effective, then how long does it last for? And how much desired are outcomes?
What the heck is that Medical Cannabis? Doctors in Florida say that Florida Medical Marijuana or Florida medical cannabis is the kind of cannabis or cannabinoids being used in various foods and medicines for human welfare. It is found powerful against sleeping disorders, neural degradation, and epilepsy. Epilepsy is a neurological disorder. Around the world, two-fifth of the people usually experience seizure attacks are the unaffected by anti-epileptic medicines hence the study has found the positive impacts of the new marijuana drugs. Prior to this, off-label cannabis plants were used by North Americans for treating a number of disorders. While, today most of the trials have been performed by Marijuana Doctors on CBD oils are being used with the epilepsy medicines hence, it remains confirmed by practitioners whether it is a potentiator of epileptic medicine or itself is anti-epileptic.
Evidences of Cannabis are useful against Seizure and Epilepsy:
The first most description of cannabis as the anti-seizure was published by Shaughnessy in the year 1843. He reported the healthy benefits of the cannabis derivatives and products on rabbits, dogs, cows, sheep, goats, cats, and many other animals. He then applied the same medications on a little baby girl (age 40 days) and also found healthy brain development. Later on, applications were applied by a number of other physicians to make medicines. Today, the use of cannabis is decreased because it is now illegal to cultivate cannabis by the general public and to misuse it.
What Components are there in Cannabis help in Seizures?
Substances named “Cannabinoids” are present in Cannabis work on the cannabinoids receptors found on the surface of the cell and generate a soothing effect. According to biological researches and various experimentation's, two main components are found that making it effective against seizures are CBD and Tetrahydrocannabinol! CBD isn’t Psychoactive but it plays an important role for betterment for some body parts while, CBD is highly responsible for bettering mental conditions, and it’s Psychoactive in nature.
Benefits of Cannabis for Seizure:
With the advancement of medicinal science, researchers keep exploring more about cannabis, and for now, it is set at the top for treating seizure and has three profound benefits:
- Epilepsy, most of the times, characterized by intense random and abnormal movement of neurons in the brain for short periods, in case, if the activity lasts for longer, brain cells may get damaged – Cannabis supports here, it has anticonvulsant properties and provides relief against seizures.
- It keeps brain from further degradation of neural cells and also prevents cells mobility. Research has made it clear that it effectively keeps a charge to regulate epilepsy seizures.
- Status Epilepsy – It is characterized by non-convulsive and convulsive seizures both. A seizure in this, lasts for 3-5 minutes, it’s very difficult for patient to regain the prior mental position and if the patient doesn’t get effective medication on-the-spot it may lead to complete loss of neural health and Death. Florida Marijuana Doctors, after having intense study found CBD oil effective against Status Epilepsy.
Report of a chemical called cannabidiol (CBD) had reduced the seizures of a 6-year-old girl from near-death levels to almost zero sent desperate patients everywhere on a frenzied quest for treatment.
According to several media outlets, a patient was suffering 300 grand mal seizures per week and had lost the ability to walk, talk, and eat. Existing epilepsy medication had failed her. But CBD—a component of cannabis that does not trigger the plant's characteristic high—reduced her episodes to a few per month, and, as her parents told reporters, ushered in a full cognitive recovery.
By most estimates, existing seizure medications fail about one-third of all sufferers, either because the drugs don't stop the seizures or because the side effects are too severe. As story spread, families with loved ones suffering from this type of epilepsy which can range from seriously debilitating to life-threatening) began relocating from states where CBD could not be legally obtained to states where it could. At least some of them reported similarly miraculous responses to it. Many Doctors in Florida and Other states are prescribing this medicine to children with great results. So when we reported earlier this month that a new National Academy of Sciences reported the most in-depth analysis of marijuana research to date concluded that there was not enough evidence to say that cannabis oil could actually treat epilepsy, some people were surprised:
How could the panel draw such a conclusion? Isn’t the patients case, and others like it, proof enough that cannabis oil can succeed for epilepsy patients where so many other treatments have failed?
Because readers asked, and because this particular conclusion one of almost 100 that the academy drew from their scientific review is a good window into the whole report and the larger debate surrounding the subject so we decided to take a closer look.
Evidence Considered By The Panel
The reviewers restricted their evaluation to studies that involved humans, excluding any evidence from studies done on animals. That decision was based on sound scientific rationale (animal, or “pre-clinical,” studies can give us important clues about how a chemical might behave, not whether it will be safe or effective for humans). But limiting the studies in this way left the reviewers with some pretty slim pickings.
There were just three clinical studies where doctors treated patients with CBD and measured whether and by how much those patients’ seizures were reduced. The largest of those studies included a total of 162 patients, treated with 99 percent CBD oil extract for 12 weeks; it found that CBD worked about as well as existing anti-epilepsy medications do in treatment-resistant sufferers.
CBD reduced seizures by a monthly average of 36.5 percent; only five patients saw their motor seizures completely disappear during the study period, and only two patients became completely seizure-free.
Why That Evidence Was Deemed Insufficient
For three reasons, mainly.
First, there was simply not enough of that kind of evidence. FDA-approved drugs are usually deemed effective or ineffective based on large-scale clinical trials that study hundreds to thousands of patients over several years. These studies followed only a few hundred patients in all, and for only a few months.
Second, the studies in question did not include placebo controls. That is, all of the study participants were given actual CBD, and they knew they were getting it. Other research has found that the placebo effect can be especially strong when it comes to cannabis. In one study, patients of families who moved to Colorado for cannabis oil treatment were twice as likely to report a substantial reduction in seizures as those patients who already lived in the state. All Natural MD offers medical marijuana doctors certifications and ID card in Florida, We have offices for medical marijuana treatment in Lakeland, Orlando, Sarasota, Bradenton, Lake Mary and Tampa.
The third major reason the studies were deemed insufficient involves drug interactions. Most of the patients in the studies we’re talking about were taking other anti-epilepsy drugs, such as clobazam and valproate, and it turns out that CBD is very good at blocking the liver enzymes that normally break down those other drugs. This drug interaction makes it impossible to say whether reduced seizure incidence seen in study participants was due to CBD by itself or whether it was simply the result of those other medications staying in the system for longer stretches.